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Rules by Cynthia Lord
Frustrated at life with an autistic brother, twelve-year-old Catherine longs for a normal existence but her world is further complicated by a friendship with a young paraplegic. (catalog summary)
If you like sometimes funny, sometimes serious books with brother-sister themes, check out these titles:
Cheating for the Chicken Man by Priscilla Cummings
High school freshman Kate has a lot on her mind, what with taking care of her heartbroken mother and looking after the family chicken farm in Maryland, but she promised her dying father to look after her older brother who is just back from juvenile detention—and this year that seems to involve paying off the bullies at school by doing their school work. (catalog summary)
Counting Thyme by Melanie Conklin
Thyme Owens moves across the country with her family so her younger brother can take part in a promising cancer drug trial, and though all she wants is for him to get better, adjusting to life in Manhattan is anything but easy. (catalog summary)
What really happened when genius businessman Sir Owain Lancaster decided he could conquer the Amazon? In the 1800s, it was not so unusual for British gentlemen to take on this kind of task—to prove the superiority of man over the elements and increase our scientific knowledge. In Sir Owain’s case, the natural elements won. Or, perhaps they were horrifically supernatural, as Sir Owain claims. Stephen Gallagher’s Bedlam Detective is determined to find out the truth.
Jason Blake isn't a "neurotypical" kid. Jason is an autistic 12-year old struggling to live in a world filled with "neurotypicals," who unsuccessfully try to understand the problems he faces in day-to-day life. In the book, Anything but Typical, Nora Raleigh Baskin demonstrates what it is like to be a sixth grader with autism.
Jason tries to express himself with others but finds that people don't like to take the time to get to know and understand him. The only place that Jason feels safe to communicate is online. There he writes and posts short stories on a Web site where young writers share their work amongst each other. There he meets Rebecca; they quickly begin helping each other with their writing. Jason strikes up a friendship with Rebecca but fears that they could never meet due to his autism.