Have You Seen Marie? is a picture book, but it is aimed at adults. The author and illustrator created it as an attempt to help them deal with their grief, for each of them has lost a parent.
The story is about Sandra Cisneros who suffered from depression after her mother’s death. Her doctor encouraged the author to take antidepressants, but she resisted taking medication. Her friend came to visit her and while there lost her cat, Marie. The act of trying to find her friend’s cat forced Cisneros out of the house and into the world again in order to help her friend. This picture book introduces all of her colorful neighbors as she tries to find Marie.