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There are a lot of powerful books around that deal with different types of abuse and addiction. The following titles focus on drug abuse specifically.
If you like Crank by Ellen Hopkins, here are some other books that you may like:
Glass (sequel to Crank) by Ellen Hopkins
In a powerful sequel to Crank, Kristina is determined to manage her addiction to crack in order to keep her newborn child, but when she is unable to manage her use of the drug and the pull becomes too strong, her greatest fears are quickly realized.
Go Ask Alice by anonymous
A powerful, fictional diary of a teenage runaway and her decent into drug abuse.
A Million Little Pieces by James Frey
Now acknowledged as fiction and not a true story, this is the author’s account of his drug addiction and rehabilitation.
The Perks of Being a Wallflower by Stephen Chbosky
Most people think 15-year-old Charlie is a freak. The only friend he had killed himself, forcing him to face high school alone. But then seniors Patrick and his beautiful stepsister Sam take Charlie under their wings and introduce him to their eclectic, open-minded, hard-partying friends. It is from these older kids that Charlie learns to live and love, until a repressed secret from his past threatens to destroy his newfound happiness.
Smack by Melvin Burgess
Like so many teenagers, Tar and Gemma are fed up with their parents. Tar's family is alcoholic and abusive, and Gemma feels her home life is cramped by too many restrictions. The young, British couple runs away to Bristol in search of freedom, and finds it in the form of a "squat." This vacant building is also occupied by two slightly older teens who share everything with Tar and Gemma (including their heroin habits). For a while, everything is parties and adventures, but slowly Tar and Gemma find themselves growing more and more dependent on the drug--whose strict mandates are even less forgiving than those of the parents they fled.
Stoner and Spaz by Ron Koertge
A troubled youth with cerebral palsy struggles toward self-acceptance with the help of a drug-addicted young woman.
Tweak: Growing Up on Methamphetamines by Nic Sheff
The author details his immersion in a world of hardcore drugs, revealing the mental and physical depths of addiction, and the violent relapse one summer in California that forever changed his life, leading him down the road to recovery.
Wintergirls by Laurie Halse Anderson
"Dead girl walking," the boys say in the halls. "Tell us your secret," the girls whisper, one toilet to another. I am that girl. I am the space between my thighs, daylight shining through. I am the bones they want, wired on a porcelain frame. Lia and Cassie are best friends, wintergirls frozen in matchstick bodies, competitors in a deadly contest to see who can be the skinniest. But what comes after size zero and size double-zero? When Cassie succumbs to the demons within, Lia feels she is being haunted by her friend's restless spirit.